Genetics and Gene Panel Testing Working Group

Date: Friday 18 October 2019
Time: 08:00 – 10:00
Chairs: Gabriel Capella (Spain), Elke Holinski-Feder (Germany)

Time Session
08:00 – 08:20 What if we would use a diagnostic multi-cancer gene panel for opportunistic screening? A study in 2,090 Dutch familial cancer patients – Maran Olderode-Berends (The Netherlands)
08:20 – 08:40 Long term follow-up and advances in genetic technologies result in improved management of families with inherited colorectal cancers – Gareth Evans (UK)
08:40 – 09:00 The Clinical Utility of Tumour Mutational Signatures for Identifying Hereditary Colorectal Cancer and Polyposis syndromes – Daniel Buchanan (UK)
09:00 – 09:08 SigProfilerWeb: a user-friendly web application for accurately determining the activities of mutational signatures – Marcos Diaz-Gay (Spain)
09:08 – 09:16 Prevalence of pathogenic variants of FAN1 among more than 5000 consecutive patients referred to one genetic clinic for suspected hereditary predisposition to colorectal, breast/ovarian or other cancers – Marine Le Mentec (France)
09:16 – 09:24 High Likelihood of actionable pathogenic variants in breastcancer genes in women with very early onset breast cancer – Gareth Evans (UK)
09:24 – 09:32 Multiple Genetic Tumor Syndromes (MGTS):when to suspect them? – Emanuela Lucci-Cordisco (Italy)
09:32 – 09:40 National recommendations of the French Genetics Cancer Group – Unicancer on the modalities of multi-gene panel analysis in hereditary predispositions to tumours of the digestive tract – Chrystelle Colas (France)
09:40 – 09:48 Somatic mosaicism by a de novo MLH1 mutation as a cause of Lynch Syndrome – Fonnet Bleeker (The Netherlands)
09:48 – 10:00 Collaborative Studies