Plenary Scientific Meeting

Friday 13 May 2016

Time Event
09:00 – 11:00 Chemoprevention and Immunotherapy
Chairs: M. v. Knebel-Doeberitz, John Burn
09:00 – 09:15 Towards a Vaccine Against MSI Cancer – M. Kloor, Magnus von Knebel Doeberitz
09:15 – 09:30 Dendritic Cell Therapy with Mutant Gene Products in MSI Cancers – Gerty Schreibelt
09:30 – 09:45 Development of Viral Delivery Systems for Cancer Vaccines – Elisa Scarselli
09:45 – 10:00 The Role of PDL1 Inhibition in MMR Deficient Tumours – Elke Jäger
10:00 – 10:15 Chemoprevention and ASS – John Burn
10:15 – 10:30 Role of Environmental Modifiers in the Risk of Colorectal Cancer for Lynch Syndrome – Aung Ko Win
10:30 – 10:38 OR09: Frameshift Mutations in Microsatellite Unstable Colorectal Cancers: from Immune Signature to Personalized Immunotherapy – Jean-Baptiste Latouche
10:38 – 10:45 Applying Simulation Modelling in Cancer Vaccine Development – Mark Coles
10:45 – 11:00 Optimizing Delivery of Cancer Vaccines: Short Peptides. Insights from Disease Modelling – Jonathan Wagg
11:00 – 11:30 Coffee Break
11:30 – 13:01 Polyposis Syndromes and Inherited Colorectal Cancer
Chairs: Ian Tomlinson, Ian Frayling
11:30 – 11:45 PPAP and NAP – Ian Tomlinson
11:45 – 12:00 Hot Topic: A New Polyposis Gene! – Stefan Aretz
12:00 – 12:15 Update JPS – Robert Blatter, Karl Heinimann
12:15 – 12:30 NGS Panel Testing – Gabriel Capellá
12:30 – 12:38 OR04: Molecular Diagnosis of Inherited Colorectal Cancer using NGS Panel – Stéphanie Baert-Desurmont
12:38 – 12:46 OR03: Functional Assays and Bioinformatics Predictions Reveal a High Contribution of Splicing Mutations in the Most Frequent Forms of Hereditary Cancer – Alexandra Martins
 12:46 – 12:49 SO04: Targeted NGS of 22 Mismatch Repair Genes Identifies LS Families – Bente Talseth-Palmer
 12:49 – 12:52  SO08: Identification of Novel Causal Genes of Hereditary Colorectal Cancer – Laura Valle
12:52 – 12:55 SO10: Identification of Genetic Biomarkers for Clinical Management of Familial Colorectal Cancer -Mev Dominguez Valentin
12:55 – 12:58 SO03: Evaluation of a 25-Gene Panel in Patients with Suspected Lynch Syndrome: Preliminary Results from the FAMOSA Study – Ariadna Sánchez García
12:58 – 13:01 SO09: Elucidating the Molecular Basis of MSH2-Deficient Tumours  in Lynch Syndrome Suspected Patients – Marta Pineda
13:01 – 13:30 Lunch Break
13:30 – 15:00 Registries and Guidelines
Chairs: Rolf Sijmons, Pål Møller, Maurizio Genuardi
13:30 – 13:45 Carriers of Path_MMR Variants: Penetrance, Expressivity and Survival – Pål Møller
13:45 – 14:00 Health Economic Principles – Ian Frayling
14:00 – 14:15 In Vitro Testing – Moni Morak, Elke Holinski
14:15 – 14:30 Potential of International Mismatch Repair Consortium (IMRC) Collaboration – Aung Ko Win
14:30 – 14:45 LOVD and Big Data Management – John Paul PlazzerFinlay Macrae
14:45 – 14:53 OR02: The LynCE study (The pilot): An assesment of endometrial cancer progression markers in Lynch syndrome – Angel Alonso Sanchez
14:53 -15:01  OR07: Age Stratified Surveillance Strategies Lynch Syndrome-Associated Cancer According to Mismatch Repair Mutation – Neil Ryan
15:01 – 15:30 Discussion: Pathway for Inclusion of Lacking Variant and Mutation Information into the LOVD – Finlay Macrae, Pål Møller
15:30 – 16:00 Coffee Break
16:00 – 18:05 Surgery, Endoscopy and Miscellaneous
Chairs: Jukka Pekka Mecklin, Gabriel Capella, Finlay Macrae
16:00 – 16:15 TaTME for Ileoanal Pouch Surgery in FAP – Potential Short and Longterm BenefitsAntonino Spinelli
16:15 – 16:30 Surgical Strategies for Pouch Surgery: Can We Improve? – Gabriela Möslein
16:30 – 16:33 SO31: Do we Still Need Surgery for Treating Small Bowel Polyps in Peutz-Jeghers Syndrome? A 13-Years Follow-up Cohort – Elia Samaha
16:33 – 16:36 SO33: Assessment of MUTYH Associated Polyposis (MAP) Phenotype in Order to Refine Testing Guidelines – Kate Simon
16:36 – 16:44 OR11: Risk Factors for the Presence of Pathogenic APC and Biallelic MUTYH Mutations in Patients with Multiple Adenomas – Maartje Nielson
16:44 – 16:47 SO30: Compliance and Impact of Colonoscopy in Familial Adenomatous Polyposis and MYH-Associated Polyposis – Carmen Guillén-Ponce
16:47 – 16:50 SO36: Incidence of Colonic Neoplasia in Patients with Serrated Polyposis Syndrome who Undergo Endoscopic Surveillance: a Multicenter Study – Sabela Carballal
16:50 – 16:53 SO34: A Reassessment Colonoscopy Increases the Diagnostic Yield for Serrated Polyposis Syndrome in a Faecal Immunochemical Test (FIT)-Based Colorectal Cancer Screening Population – Maria Pellisé
16:53 – 16:56 SO35: DNA-Diagnostics of Familial Adenomatous Polyposis and Peutz-Jeghers Syndrome Among Russian Patients – Natalia Pospekhova
16:56 – 16:59 SO01: Germline Mutations in MMR Genes Among Russian Patients with Lynch Syndrome – Alexey Tsukanov
16:59 – 17:02 SO06: Impact of an Optimized Colonoscopic Screening Program for Patient with Lynch Syndrome. Four Years Results of a Specialized French Network – Elia Samaha
17:02 – 17:10 OR12: Chromocolonoscopy with Indigo Carmine Facilitates High Adenoma Detection in Lynch Syndrome Patients – Robert Hüneburg
17:10 – 17:18 OR05: Non-Polypous Colorectal Cancer – a Distinct Tumour Type in Lynch Syndrome? – Aysel Ahadova
17:18 – 17:21 SO11: Endoscopic Surveillance of the Upper Gastrointestinal Tract in Lynch Syndrome Patients – Robert Hüneburg
17:21 – 17:24 SO02: DNA Mismatch Repair Genes Deficiency is a Frequent Phenomenon in Small Intestine Adenocarcinoma – Adriana Sanchez Garcia
17:24 – 17:27 SO22: Colon Polyps Prevention and Associated Gut Microbiota Changes in a Colorectal Cancer Animal Model fed with Functional Meat Foods Containing Prebiotics – Felipe Lombó
17:27 – 17:35 OR06: DiagMMR: Functional Lynch Syndrome Carrier Testing from Skin – Minttu Kansikas
17:35 – 17:43 OR01: Universal Screening of Colorectal Cancers for Lynch Syndrome by Reflex Immunohistochemistry – a Single Centre 9 Year Experience – Eanna Ryan
17:43 – 17:46 SO05: Selective and Universal Screening Strategies for Lynch Syndrome: a Perspective from The Royal Marsden Hospital – Bianca Desouza
17:46 – 17:49 SO29: Screening of 274 Familial Colorectal Cancer Patients Using a Multi-Gene Panel – Wenche Sjursen
17:49 – 17:57 OR10: Technological Innovation in Hereditary Cancer Risk Assessment – Anju Kulkarni
17:57 – 18:05 OR08: Young Adult Colorectal Cancer Incidence Trends in Europe: An Important Clinical and Research Opportunity for the European Hereditary Tumour Group – Thomas Weber

 

Top