Abstracts

Please see a list of successful abstracts below:

• N01: The German HNPCC Consortium: Aims, Structure, Methods and Data
• N02: Opportunities For Collaboration: Analysis Of Longitudinal Data In Lynch Syndrome Carriers To Inform Development And Calibration/Validation Of A New LS Screening Model – “Policy1-Lynch”
• N03: Prevalence, Phenotype And Clinical Consequences Of Mosaicism In APC And Other Colorectal Cancer And Polyposis Associated Genes
• N04: Breast Cancer Pathology And Stage Are Better Predicted By Risk Stratification Models Including Mammographic Density And Common Genetic Variants
• N05: Exogenous And Endogenous Associated Factors To Early Onset Colorectal Cancer
• N06: The effectiveness and the cost-effectiveness of systematic testing for Lynch syndrome in incident colorectal cancer cases in Australia
• N07: Cancer Risks By Age And Gender And Survival After Cancer In Path_MSH6 Carriers: A Prospective Lynch Syndrome Database (PLSD) Report
• N08: The Apparent Genetic Anticipation In PMS2-Associated Lynch Syndrome Families Is Explained By Birth-Cohort Effect
• N09: Worldwide Study Of Cancer Risks For Lynch Syndrome: International Mismatch Repair Consortium (IMRC)
• N10: Breast Cancer Risk In Neurofibromatosis Type 1 Is A Function Of The Type Of NF1 Gene Mutation: A New Genotype-Phenotype Correlation.
• N11: A Dominantly Inherited 5’UTR Variant Causing Methylation Associated Silencing of BRCA1 As A Novel Cause Of Breast And Ovarian Cancer
• N12: The Role Of RNF43 In Serrated Polyposis And Colorectal Cancer Predisposition
• N13: Identification Of Genetic Variants In Early-Onset And Familial Cancers By Targeted Next Generation Sequencing
• N14: Identification And Characterization Of An Alu Element Insertion In BRCA2 In A Spanish Family Associated To Prostate Cancer
• N16: Colorectal Cancer Risk Susceptibility Loci In A Swedish Population
• N17: BRF1, A Novel Gene Associated With Hereditary Colorectal Cancer
• N18: Deciphering The Contribution Of Recently Proposed Polyposis Predisposing Genes
• N19: Colorectal Cancer Risk Is Not Increased In NTHL1 Heterozygous Mutation Carriers
• N20: A New Approach In Panel Testing For Hereditary Cancer: Phenotype-Derived With Opportunistic Screening Of Mismatch Repair Genes And BRCA1 And BRCA2
• N21: Detection of a pathogenic variant on Partner and Localiser Breast cancer 2 (PALB2) gene in Lynch Syndrome family
• N22: Family Case Of Rare MSH6 Variant Identified As Secondary Finding – Shall We Screen For Lynch?
• N23: Digestive Burden Of CMMRD (Constitutional Mismatch Repair Deficiency) Patients And Overlap With Lynch Syndrome: Report From The European Care4CMMRD Consortium
• N24: Systematic Linkage Of All Diagnostic Hereditary Cancer Genotypes To The National Cancer Registry
• N25: Frequency Of Germline Pathogenic Variants Of Cancer Susceptibility Genes For Japanese Ovarian Cancer Patients
• N26: Consensus For Genes To Be Included On Cancer Panel Tests Offered By UK Genetics Services: Guidelines Of The UK Cancer Genetics Group
• N27: The Management Of Gynaecological Cancers In Lynch Syndrome: The Manchester International Consensus Meeting
• N28: Awareness Of Lynch Like Syndrome Within Clinical Genetics –Results From A UK Survey
• N29: New Treatment Possibilities For Lynch Syndrome-Associated Cancer?
• N30: Life-Long Immune Surveillance And Immunoediting – Evidence From Lynch Syndrome Cancers
• N31: Identification Of Clinical, Genetic And Endoscopic Predictors Of Incident Colorectal Cancer In Lynch Syndrome
• N32: A Novel Mainstreaming Model For Lynch Syndrome Genetic Testing In Colorectal Cancer Patients
• N33: Validation And Updating Of Path_MLH1 In Cases With Class 4 And 5 Genetic Variants; A Prospective Lynch Syndrome Database (PLSD) Report
• N34: A Functional Assay-Based Procedure To Classify Mismatch Repair Gene Variants In Lynch Syndrome
• N35: An Assessment Of Endometrial Cancer Risk Markers In Lynch Syndrome Patients
• N36: Back To Back Comparison Of Colonoscopy With Virtual Chromoendoscopy Using Third Generation Narrow Band Imaging System To Chromoendoscopy With Indigo Carmine In Lynch Syndrome Patients
• N37: Cancer Incidences By Age In Path_PMS2 Carriers: A Report From The Prospective Lynch Syndrome Database (PLSD)
• N38: Yield Of Lynch Syndrome Surveillance For Individual MMR Genes
• N39: The Prospective Lynch Syndrome Database (PLSD)
• N40: Validated And Updated Risks For And Survival After Cancer By Age And Gender In Path_MSH2 Carriers; A Prospective Lynch Syndrome Database (PLSD) Report
• N41: Small Bowel Neoplasia Detection In Lynch Syndrome Using Video Capsule Endoscopy
• N42: Improving Triaging Of Patients With Sebaceous Neoplasia For The Identification Of Muir-Torre/Lynch Syndrome
• N43: Hide And Seek With Hereditary Cancer: Testing The Effectiveness And Cost-Effectiveness Of Implementation Approaches For Translating Lynch Syndrome Evidence Into Practice
• N44: Genetic And Clinical Characteristics Of Registry-Validated Pedigrees Of Lynch Syndrome Families In Slovenia – First Report
• N45: High-Definition White-Light Colonoscopy Versus Chromoendoscopy For Surveillance Of Lynch Syndrome. A Multicenter, Randomized And Controlled Study (Endolynch Study)
• N46: The Role Of Immunohistochemistry (IHC) Testing In The Tumor Spectrum Of The Lynch Syndrome (LS)
• N47: Prevalence Of Mismatch Repair Deficiency In Small Bowel Carcinomas And Neuroendocrine Tumours
• N48: Molecular Tumor Testing In Lynch-Like Patients Reveals De Novo Mosaic DNA Mismatch Repair Gene Pathogenic Variants Transmitted To Offspring
• N49: A Mouse Model For Proof Of Concept Of A Vaccine Against Lynch Syndrome-Associated Cancers
• N50: Age-Related Efficiency Of BRAF V600E Mutational Testing For The Exclusion Of Lynch Syndrome In MSI Colorectal Cancers
• N51: A Novel Tool For Quantitative Analysis Of Microsatellite Mutations And Frameshift Neoantigens
• N52: MMR Deficiency Is An Early Event In Lynch Syndrome Colorectal Cancer Pathogenesis
• N53: Discordant IHC MMR Staining And MSI Results In Tumors Of MSH6 Mutation Carriers
• N54: Characterisation Of Mismatch Repair Variants Submitted To The International Mismatch Repair Consortium (IMRC)
• N55: A Genetic Variant In Telomerase Gene Modifies Cancer Risk In Lynch Syndrome Patients Harbouring MSH2 Mutations
• N56: Incorporating Somatic Sequencing Into Current Molecular Testing Strategies For Lynch Syndrome
• N57: Comprehensive Constitutional (Epi)Genetic Characterization Of Lynch-Like Patients
• N58: The Cost Of Identifying Lynch Syndrome Carriers In Australia
• N59: Highly Sensitive MLH1 Methylation Analysis In Blood Allows The Identification Of Low-Level Epigenetic Mosaicism
• N60: Lynch Syndrome Registries In Latin America
• N61: Physical Activity And The Risk Of Colorectal Cancer In Lynch Syndrome
• N62: Genetic And Clinical Features In Russian Patients With Lynch Syndrome
• N63: Clinical And Molecular Characterization Of Lynch-Like Syndrome
• N64: Peritoneal And Abdominal Wall Metastasis Following Colectomy In A Patient With Lynch Syndrom. Is It Time To Rethink The Non-Metastatic Theory?
• N65: Etiology And Characterization Of Lynch-Like Syndrome Patients
• N66: The ICCon Australian Database Of Mismatch Repair Variants
• N67: Penetrance For Carriers Of A DNA Mismatch Repair Gene Specific Variant
• N68: A Multidisciplinary Approach To Familial Pancreatic Cancer Enriches The Proportion Of Patients With Pancreatic Cancer Susceptibility
• N69: Interpretation Of Inheritable DNA Variation: Room For Error Across Genetic Services?
• N72: CSTF2T And ACTB Discern Sporadic From FAP-Associated Colon Carcinomas At Various Stages Of Carcinogenesis On The Proteomic Level
• N73: The Danish HNPCC-Register From 1991 To 2018
• N74: Idiopathic Pan-Colonic Varices Found Incidentally In A Young Patient With A Hepatic Flexure Tumor: A Rare Occurrence And A Challenging Surgical Management
• N75: Hereditary Cancer Predisposition Syndromes: Evaluation On The Influence Of Personality In Predictive Genetic Testing
• N77: Correlation Of Immunohistochemical Mismatch Repair Protein Status In Colorectal Carcinoma Endoscopic Biopsy And Resection Specimens
• N78: In Contrast To Subjects With Lynch Syndrome, The Adenomatous Polyps From Subjects With Sporadic MSI-High Tumors Have Normal Expression Of MMR Proteins
• N79: Immune Microenvironment Of Colorectal Carcinoma
• N80: An International Study Of Duodenal Disease In MAP: Incidence Of Polyposis And Cancer
• N81: Genomic And Transcriptomic Profiling Of Duodenal Adenomas In Familial Adenomatous (FAP) And MUTYH-Associated Polyposis (MAP)
• N82: Endocuff-Assisted Colonoscopy Versus Standard Colonoscopy In The Surveillance Of Serrated Polyposis Syndrome. A Randomized, Controlled And Multicenter Study
• N83: Surveillance Recommendations For First-Degree Relatives Of Patients With Unexplained Multiple Colorectal Adenomas: A Nationwide Survey Of UK Regional Genetic Services
• N84: Mutations In MutYH Gene Among Russian Patients With Colorectal Polyps
• N87: SELINA – Clinical Trial On Lowering The Risk Of Malignancies By Optimizing Selenium Levels In Females From Families With Hereditary Breast Cancer
• N88: The National Lynch Syndrome Registry of Finland (LSRFi)
• N89: Microsatellite instability analysis and NGS with fragmented sample types
• N90: Argentinean Lynch syndrome registry: Experience from Rosario
• N91: Hereditary Cancer Program (ProCanHe): 21 years of experience at a referral registry In Argentina
• N92: Chilean Hereditary Colorectal Cancer Registry: Experience from Clinica Las Condes
• N93: Hereditary Gastrointestinal Cancer Mutational Registry in Uruguay
• N94: Uruguayan Hereditary Breast and Ovarian Cancer Syndrome Registry: BRCA and Non-BRCA pathogenic variants
• N95: Screening of hereditary CRC at a Chinese cancer center
• N99: Identification of mismatch repair-deficient colorectal cancers using a molecular inversion probe based sequencing assay of short mononucleotide repeats