Working Group – Pathology and Immunology

Date: Tuesday 25 September 2018
Time: 08:00 – 10:30

Time	Session
08:00 – 08:30	Towards a vaccine against microsatellite-unstable cancers – Magnus von Knebel Doeberitz (Germany)
08:30 – 09:00	N30: Life-long immune surveillance and immunoediting – evidence from Lynch syndrome cancers – Matthias Kloor (Germany)
09:00 – 09:30	The balance between cytotoxic T-cell lymphocytes and immune checkpoint expression determines prognosis in colon tumours – Alex Duval (France)
09:30 – 09:40	Discussion
09:40 – 10:30	Pathology and Immunology Abstracts (8 mins for presentation + 4 mins for questions)
09:40 – 09:52	N29: New treatment possibilities for Lynch syndrome-associated cancer? – Christina Therkildsen (Denmark)
09:52 – 10:04	N78: In contrast to subjects with Lynch Syndrome, the adenomatous polyps from subjects with sporadic MSI-high tumours have normal expression of MMR proteins – Zohar Levi (Israel)
10:04 – 10:16	N48: Molecular tumor testing in Lynch-like patients reveals de novo mosaic DNA mismatch repair gene pathogenic variants transmitted to offspring – Chrystelle Colas (France)
10:16 – 10:28	N51: A novel tool for quantitative analysis of microsatellite mutations and frameshift neoantigens – Alexej Ballhausen (Germany)